Myocardial arterial spin labeling

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Myocardial arterial spin labeling.

Arterial spin labeling (ASL) is a cardiovascular magnetic resonance (CMR) technique for mapping regional myocardial blood flow. It does not require any contrast agents, is compatible with stress testing, and can be performed repeatedly or even continuously. ASL-CMR has been performed with great success in small-animals, but sensitivity to date has been poor in large animals and humans and remai...

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Myocardial perfusion using arterial spin labeling CMR: promise and challenges.

c i d B t Arterial spin labeling (ASL) magnetic resonance imaging (MRI) is a noncontrast technique that can quantify tissue blood flow. It is most commonly applied to the brain (1) and kidney (2); however, it also has potential application to other organs, including the heart (3). Used for the heart, ASL might eventually play a role in cardiac pharmacological stress testing, where it could be u...

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Qualitative and quantitative myocardial perfusion with arterial spin labeling

Introduction A reduction of myocardial blood perfusion is the main physio-pathologic mechanism determining ischemic heart disease. Whilst SPECT and echocardiography are considered the reference standards for imaging perfusion defects, MRI techniques are emerging. Dynamic imaging of the first-pass of a contrast agent is currently the most frequently used of these techniques, however, guidelines ...

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Myocardial arterial spin labeling perfusion imaging with improved sensitivity

BACKGROUND Myocardial arterial spin labeling (ASL) is a noninvasive MRI based technique that is capable of measuring myocardial blood flow (MBF) in humans. It suffers from poor sensitivity to MBF due to high physiological noise (PN). This study aims to determine if the sensitivity of myocardial ASL to MBF can be improved by reducing image acquisition time, via parallel imaging. METHODS Myocar...

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Demonstration of velocity selective myocardial arterial spin labeling perfusion CMR

Background Arterial spin labeling of the heart has been shown to estimate myocardial perfusion and perfusion reserve at a single short-axis slice for coronary artery disease assessment. However, current spatial labeling methods suffer from transit delay effects when imaging is extended to more than a single slice. Velocity selective (VS) labeling is a promising alternative that does not suffer ...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2016

ISSN: 1532-429X

DOI: 10.1186/s12968-016-0235-4